Dermal Scar Modes
Remodeling the Dermis of Scars:
- remove old excessive, disorganised collagen with collegenase
- replace with new properly organized collagen
- regain near orginal structural strength
- Manipulation of Fibroblast through the intercellular calcium
- Skin tension management through taping, and splinting
- Collegenase enhancement with Hyper-heal cream.
The Dermis and Scar physiology
- induce macrophage activity and healing cascades -silicone
- induce collagenase production - silicone sheet, Hyper-Heal
- prohibite collagense over-production hyper-Heal , siliocne
- induce collagen production silicone, Hyper-Heal cream
- inhibite collagen over-production- silicone
- induce micro injury induce healing response - dermal needling
Dermis structure and function
- 80% of skin structural strength
- cytokine staging
- main cell - fibroblast (gogli complex)
- other cells- macrophage, blood, mast
- protein matric is collagen basket weave pattern
- protein matrix breadown enzyme collegenase
- calcium levels and skin tension drive remodeling cycle
- Phosphatydalcholine main substrate
- cholesterol, cermaides drive kinases healing cascades
- copper, zinc, magnisium, phosphorus, iron ions enzyme catalyst